ONE lane has been reopened on the Peak Downs Highway.
Motorists are asked to drive with care and abide by the temporary traffic controls in place.
For further updates on road conditions call 131 940.
Two patients have been transported to Moranbah Hospital following the crash.
A 45-year-old woman has been taken in a serious condition with chest pain and multiple leg fractures and a 20-year-old man has been taken stable to Moranbah Hospital with facial injuries, the Queensland Ambulance Service said.
Meanwhile the Bruce Hwy about 10km north of Bowen is now open after a two-vehicle crash.
A police spokesman said the crash occurred about 5.45am and one person suffered minor injuries.
One person is believed to be entrapped in a vehicle after a three-vehicle crash this morning.
Emergency services are still on scene as the highway remains shut, a police spokesman said.
He said the crash had involved two vehicles and a B-double on the Peak Downs Hwy in the Red Hill area of Moranbah.
A Queensland Fire and Emergency Service spokeswoman said they received the call to attend about 3.40am.
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